CiPA Work Streams
Develop voltage clamp protocols for core set of cardiac ion channel types.
Develop consensus in silico model to reconstruct electrophysiologic activity within a heart cell.
Investigate capabilities of human stem-cell derived cardiomyocyte assays to confirm findings of in vitro and in silico assays.
Human Phase I ECG
Use human phase 1 ECGs to evaluate potential unanticipated effects.